Nexus - 1904 - New Times Magazine-pages

Page Content (OCR)

Even stress intolerance can be due to a CYP450 Often the opposite occurs. Here again, specific CYP450 anomaly. This is because these enzymes process adrenal enzymes are activated by specific vitamins or herbal hormones. For some people, the smallest stress makes compounds. But if these specific CYP450s are defective them feel very ill because the increased level of adrenal or deficient, these herbal compounds or supplements hormones induces specific CYP450 enzymes. If these are may build up to toxic levels and/or induce the creation of deficient, the adrenal hormones can build up to oxic levels of porphyrins again. dangerous levels or at least to a level that the person This may be an unspoken but common occurrence in walks around with "the shakes". Thus this mechanism he patients of alternative practitioners. Because either may account for numerous seemingly "emotional" or no type of testing occurs beforehand for supplements or "mental" illnesses. he testing—including muscle testing—is not accurate, The notion of defective CYP450 enzymes may relate to he patient continues to react adversely to assumed he person having (usually hidden) porphyria. Recall beneficial supplements. For 32 years I have had people NEXUS 18/01] that in porphyria—which I stated that bring up to hundreds of supplements for testing. This some 20 per cent of us may have a genetic predisposition culminated in 2002 with my creating specia or—attempts to increase production of haem inesiological testing to determine if foods or compounds often end up causing an increase in the level supplements will elicit adverse reactions via the of circulating porphyrin compounds. This then causes mechanism discussed in this article. Some people tes much illness and suffering. It is heavy metal or other _ badly for 98 per cent of their supplements. One mistake oxic exposure that if high enough or if long-lasting hat supplement companies make is to play the one- enough can cause a permanent upmanship game and try to add CYP450 problem. This is really more ingredients than their porphyria, but "the powers that 9 competition does, thus causin be" do not want the word If a substance Ina food one or more ingredients to react orp nya to ne Re attempts to activate a adversely the 20 probably because they do no cs . you are among the 20 per want us to realise the extent s ecific CYP450 that IS cent that this applies to , pp , poset deliberteness and | deficient or defective, conser ‘oking supplemens rom the toxic exposures to the food compound ma capsules with little or no Pst which we are subjected. One not be detoxified... excipients and perhaps with only example of this is that most the one nutrient that you wish to pesticides are created to take. Also, the person with overwhelm and destroy the deficient or defective CYP450 CYP450 enzymes in plants—but because our CYP450s are — enzymes may have to take supplements in a very different virtually identical, pesticides at any level are harmful to — way. If you can take them at all, try taking smaller amounts and umans. Eating organic is wise. rotate them—i.e., take your supplements only every 4—5 days or so. But know that some people cannot take any vitamin or CYP450 Enzymes, Foods and Drugs herbal supplement. Homeopathic remedies may also be We will also see that individual CYP450 anomalies — problematic either because of reaction to the alcohol, account for allergy-like reactions to specific foods in lactose or sucrose or because the remedy is not dilute many people. This is because the CYP450 enzymes enough for these people. process specific compounds in various foods. If a The need to rotate supplements mirrors the need to do substance in a food attempts to activate a specific likewise with foods in people with these CYP450 CYP450 that is deficient or defective, the food compound anomalies. Indeed, microscopic CYP450 anomalies may may not be detoxified and may build up to a toxic level in again explain the macroscopic problems of universal food he body and/or again may lead to toxic levels of reactivity, addiction and withdrawal. Food addiction is a porphyrins circulating as well. This effect accounts for rampant problem. Sometimes a specific substance why skin or blood tests often do not find evidence of food _—_ added to food is notoriously addictive, as is the case with "allergies" in these people. It is not an antibody-antigen | monosodium glutamate (MSG). Other times, specific reaction but a metabolic one. Indeed, if a slight natural food components in these foods cause an adverse immunological reaction does also ensue, this can cause reaction—and, in the early stages, sometimes an ar greater harm than expected because another CYP450 = addiction—and a withdrawal phase. Once a set of enzyme that processes histamine may also be deficient or | CYP450 enzymes is induced (or attempted to be induced) defective. by a specific food component, the effects of this Another now common phenomenon that the CYP450 —_— induction can be felt for several days due to the anomaly accounts for is that many people taking vitamins —_ individual CYP450 enzyme's half-life (1-4 days) and/or the or herbs do not see improvement. time needed to clear the body of excess porphyrins. attempts to activate a specific CYP450 that is deficient or defective, a c the food compound may not be detoxified... CYP450 Enzymes, Foods and Drugs We will also see that individual CYP450 anomalies account for allergy-like reactions to specific foods in many people. This is because the CYP450 enzymes process specific compounds in various foods. If a substance in a food attempts to activate a specific CYP450 that is deficient or defective, the food compound may not be detoxified and may build up to a toxic level in the body and/or again may lead to toxic levels of porphyrins circulating as well. This effect accounts for why skin or blood tests often do not find evidence of food "allergies" in these people. It is not an antibody-antigen reaction but a metabolic one. Indeed, if a slight immunological reaction does also ensue, this can cause far greater harm than expected because another CYP450 enzyme that processes histamine may also be deficient or defective. Another now common phenomenon that the CYP450 anomaly accounts for is that many people taking vitamins or herbs do not see improvement. 38 * NEXUS JUNE - JULY 2012 If a substance in a food www.nexusmagazine.com