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Candida infestations are linked to the indiscriminate mass use of antibiotics. Until the introduction and mass use of antibiotics, there were no problems with candidiasis. However, in the 1950s and 1960s, the published information on candidiasis started filling orthodox medical journals, highlighting yet another serious, doctor-caused, scourge of humanity and its link to the mass use of antibiotics. Orthodox medicine and its toxic medications (vaccines and antibiotics) are also lurking behind the well-documented and indisputable pandemics of obesity and diabetes—but that's for another article. Candida infestations are linked to the indiscriminate provided no advantage. Even without a major re- mass use of antibiotics. Until the introduction and evaluation of their results, Mandel et al. demonstrated mass use of antibiotics, there were no problems with hat amoxicillin has a very poor efficacy indeed. candidiasis. However, in the 1950s and 1960s, the Perhaps it is worth mentioning that those with published information on candidiasis started filling persistent middle-ear effusion at the end of the four- orthodox medical journals, highlighting yet another week end-point were dismissed from the study. The serious, doctor-caused, scourge of humanity and its link — placebo was only described as similar in appearance to the mass use of antibiotics. and taste as the active medication and contained the Orthodox medicine and its toxic medications — same inert ingredients. (vaccines and antibiotics) are also lurking behind the As an aside, it is interesting that further studies show well-documented and indisputable pandemics of hat viruses, such as respiratory syncytial virus (RSV), obesity and diabetes—but that's for another article. ave been identified in the middle-ear fluid of children with acute ear infections (Heikkinen et al., 1999). RSV— The Cantekin Affair originally called chimpanzee coryza virus, a Just how effective are antibiotics in contaminant of polio vaccines the treatment of otitis media with produced on captive laboratory effusion (OME, a sticky fluid behind chimpanzee kidneys—has_ been the eardrum in the middle ear, but I d d known since the 1950s and 1960s to with no ear infection)? Of special ndee 5) be the cause of severe coryza in interest is the question of the Cantekin et al. captive chimpanzees. It spread to effectiveness or otherwise of millions of children who were the amoxicillin, one of the most showed that the recipients of such contaminated polio prescribed antibiotics in the recipients of vaccines. The virus was renamed RSV treatment of OME, or secretory otitis oe to cover up its connection to media (SOM). amoxicillin were contaminated polio vaccines. The Mandel et al. (1987) evaluated the two to six times presence of viruses would further efficacy of a two-week course of . explain why antibiotics are no amoxicillin trihydrate (40 milligrams more likely to efficient in treating ear infections. per kilogram of body weight per day) So, back to amoxicillin. Briefly, in a randomised, double-blind, have another biomedical engineer Erdem |. placebo-controlled trial involving bout of effusion Cantekin, PhD, and colleagues re- 518 infants and children who had ° examined the data and OME, or SOM, with and without compared with conclusions of the Mandel et al. a four-week course of oral those who study. The re-examination decongestant-antihistamine in . (Cantekin et al., 1991) showed: combination. To summarise, the were given no "Amoxicillin with and withou rate of resolution of middle-ear effusion was twice as high in hose treated with amoxicillin, either with or without the decongestant-antihistamine combination is not effective for the treatment of persisten asymptomatic middle-ear decongestant-antihistamine, as effusions in infants and children.” in those who received the Indeed, Cantekin et al. showed placebo, but 69.8 per cent of the amoxicillin-treated hat the recipients of amoxicillin were two to six times subjects still had effusion at least in one ear at four more likely to have another bout of effusion compared weeks. Side effects were reported more often in _ with those who were given no treatment. subjects who received the decongestant-antihistamine When the paper by Cantekin et al. was finally han in those who did not. Among the subjects withou published in JAMA in 1991, four years after its firs effusion at the four-week end-point, recurrent effusion | submission, Drummond Rennie, MD, the then editor o developed in one or both ears in approximately half o he Journal of the American Medical Association, added his hose in both the amoxicillin and the placebo groups own five-page editorial under the title "The Cantekin during the subsequent three months (61 percent within Affair" (Rennie, 1991). Dr Rennie described one month). Moreover, among subjects withou disagreements that had arisen between Dr Cantekin and effusion at the four-week end-point, approximately hal is fellow investigators within the Department o of those in both the amoxicillin and the placebo groups = Otolaryngology at the Children's Hospital of Pittsburgh, had a recurrent effusion within 16 weeks after Pennsylvania. Not only had Cantekin been fired from treatment. The addition of the decongestant- is job in August 1986, but others had refused to antihistamine combination to the treatment regime publish his competing 1986 re-evaluation of the by- treatment. Indeed, recipients of amoxicillin were more likely to have another compared with those who treatment. 44 «NEXUS Cantekin et al. showed that the two to six times bout of effusion were given no AUGUST - SEPTEMBER 2011 www.nexusmagazine.com