Nexus - 1603 - New Times Magazine-pages

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Cordyceps has been shown to improve libido and be important in a very specific way. The structure of quality of life in men and women, fight infertility and DNA depends on this oxygen to create the bond increase sperm count and survival. Clinical studies | between adjacent nucleosides. This bond is between involving 189 male and female patients with decreased __ the 3' and the 5' positions on the ribose portions of the libido and desire showed improvement of symptoms in nucleosides, effectively forming the "ladder structure" 66 per cent of cases. A that holds the DNA together. double-blind study conducted by the Institute o In the replication of any cell, the first step is the Materia Medica in Beijing showed an 86 per cen separation of the DNA molecule down the middle, like improvement in female libido and desire. The mos unzipping, between the pairs of complementary dramatic physical proof came from a fertility study nucleosides. involving 22 males which showed that, after eigh The next step is the insertion, one at a time, of new- weeks of taking a Cordyceps supplement, their sperm complement nucleosides. These form hydrogen bonds count increased by 33 per cent, their incidence o between the complement pairs and phosphate-sugar sperm malformations decreased by bonds between the 3' and 5' 29 per cent and their sperm survival positions at the outside edge of the rate increased by 79 per cent. molecule, which is the ribose ¢ Reverses HIV portion. In a study in 2004 in Ghana, 3,000 The synthesis of the new DNA early-stage HIV patients were given a . . molecules proceeds with the formula with Cordyceps sinensis as a There is evidence sequential insertion of new- pra mteient Boone anyones of another =| samolsmert nucleosides one ot months all 3,000 patients showed "no mechanism at play molecule until the original strand o When an HIV-AIDS patient took the | i the Cordyceps | 222 Sands being an exact copy ¢ Immune-Assist drug for cancer, their anti-tumour the original and forming the genetic clinical picture improved code for a new generation of cells. dramatically in regard to the HIV response besides This synthesis continues to proceed infection. the well-known with the insertion of each new : dulati nucleoside, unless a 3'- Immune Function, Anti-cancer Immune modulation deoxyadenosine (cordycepin Response and DNA Repair triggered by the molecule is pulled in. It has long been understood 9 When this happens, there is no that the beta-glucan compounds polysaccharide oxygen present at that vita found in many species of compounds. position to form the 3'-5' bond, mushroom significantly enhance immune function. This class of compounds is the most widely prescribed class of anticancer medications in the world. The pharmaceutical drugs lentinan, PSK and grifolan are examples of and the replication of the new DNA molecule stops. Once the DNA synthesis stops, the cel cannot continue to divide and no new cell is formed. (In normal mammalian cells, this insertion of the de-oxygenated these compounds. adenosine is of little importance, There is evidence of another mechanism at play in as healthy cells have an inherent DNA repair the Cordyceps anti-tumour response besides the well- | mechanism.) known immune modulation triggered by the When this sort of error occurs, the altered nucleoside polysaccharide compounds. It is related to the (the cordycepin) is removed from the string of structure of at least some of the altered nucleosides nucleosides and a new segment of adenosine is found in Cordyceps, exemplified by the cordycepin inserted. However, by their very nature, cancer cells compound (3'-deoxyadenosine). have lost this DNA repair mechanism. (If they could This is a molecule almost identical to normal correct their DNA errors, they would not be cancer adenosine, with the exception that it is lacking an cells.) oxygen atom on the ribose portion of the molecule at Most bacteria and all viruses (including the human the 3' position. immunodeficiency virus, HIV) lack this DNA repair The same lack of this 3' oxygen can be seen in other — mechanism. Cordyceps compounds such as dideoxyadenosine. The When we look at the rate at which cancer cells lack of oxygen at this particular position is thought to replicate, it is clear how this mechanism could exert a new- of another anti-tumour response besides the well-known triggered by the polysaccharide compounds. NEXUS ¢ 27 There is evidence mechanism at play in the Cordyceps immune modulation APRIL - MAY 2009 www.nexusmagazine.com