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Other Conditions Benefit From B12 Replenishment and what percentage is idiopathic." Almost all of his uni- and Besides Alzheimer's disease, B12 ("cobalamin"*) deficiency bipolar patients have had B12 levels in the lowest one-third of the can also cause the following conditions. And when started early, so-called normal (to prevent pernicious anaemia) range—levels replenishing B12 (i.e., restoring it to or near to levels found at that he now regards as deficient for adequate affective, cognitive birth) may often sig ‘antly improve these afflictions as well: and other mental functions. When their levels have been raised to * Depression. Often in mild form, depression can be one of the the highest one-third of that "normal" range, every one of those first clues foretelling dementia. '*"’ Chris Reading, BSc, patients felt better. For some patients who came out of their DipAgSc, MBBS, of Australia concurs: "...in most cases of [not depression or mood-swing disorder, this was the only new or only mild but also] ‘intractable depression’, a subtle B12, or other different treatment they received. In subsequent instances when nutrient, or thyroid hormone, deficiency has been missed."”*! their affective disorder worsened, B12 levels had again dropped. Psychotic depression has been particularly associated with B12 So, would restoring ample serum B12 levels prevent many or deficiency.” most of those adverse conditions? Evidence shown below, Dr As I'll discuss later, success of B12 therapy against depression Dommisse cautiously suggests, means, "Yes, at least in the case in its various forms is "probable". of depression". * Paranoid psychosis. This nutritional There is no maximum allowable age to deficit has also been linked to paranoid begin B12 therapy. Everyone loves an characterised by _ over- anecdote. A friend told me her 90-year-old ss and delusions of grandeur or live-in mother was beginning to think less persecution.” clearly than in the past and to feel a bit ¢ Bipolar-1 disorder (manic depression), depressed. I suggested: "If your dear marked by alternating periods of elation and . . mother would like to stop her incipient depression; and more commonly bipolar-2 Having a quality downward slide, let her start the therapy." by swings of mood but within normal | @BOFALOrY Measure | ener eis to old totum one's health limits.* °° serum B12 Is an around and begin to make life fun again. * Chronic fatigue syndrome.””*” essential part of the After a few weeks on high-dose B12 she ¢ Weakened immunity. Weakened . was out in the woods with her daughter immunity can lead to susceptibility to replenishment process. gathering items of interest. But three years rear non: and-ans 2 ve! gw Simply supplementing ugg! sh "eli eble’ for want of disease, cancer” and much more by a B12 "in the dark authoritative study, Your Body's Many second pathway: hindering could miss the Cries for Water, states that chronic mark badly. remethylation of the toxic sulphur dehydration is the cause of AD). amino acid homocysteine back into the Having a quality laboratory measure nontoxic essential amino acid serum B12 is an essential part of the methionine.*! replenishment process. Simply ¢ Asthma. Incomplete digestion of supplementing B12 "in the dark" could foods due to hypochlorhydria and low miss the mark badly. And to really pepsin production (see below) can be know the patient's whole picture, involved in a subsequent allergic Sherry A. Rogers, MD, suggests the response in asthma.” ION (Individualised Optimum * Disrupted sleeping/waking Nutrition) Panel is well worth its cost rhythms.” * (currently, about US$600; in the USA, ¢ Environmental illness.** contact NEEDS on 1800 634 1380).° ¢ Low stress tolerance.” The normal range for serum B12, states Dr Dommisse, should * Osteoporosis.” be defined as 600 to 2,000 pg/mL. Japan's "normal" range is + AIDS (acquired immuno-deficiency syndrome).* 500-1,300.°! According to Dommisse, this may explain why ¢ Premature ageing.” Japan has such a low rate of Alzheimer's dementia® compared to ¢ Multiple sclerosis.*“*! Symptoms of MS have been noted in the USA.* By some estimates, as many as 80 per cent of elderly persons with a vitamin B12 deficiency prior to evidence of American patients may share hidden B12 insufficiency. *° megaloblastic anaemia. There is a remarkable epidemiologic Also, B12 deficiency is common with folate deficiency in similarity between MS and pernicious anaemia, and similar HLA dementia” *’ and worsens over time as the deficiency increases.” (human lymphocyte antigens) are suggested for the association of | The impact was seen first on neuropsychiatric measures; the two conditions. augmentation of B12 and folate materially improved scores on + Alzheimer's mimicking and non-Alzheimer's dementia.” cognitive performance tests.°" (* The name "cobalamin" has been advocated because the large Intramuscular injection of B12 also has yielded seeming B12 molecule includes a cobalt molecule; see W. S. Beck, miracle cures in still other desperate illnesses. Further, in "Cobalamin and the nervous system" [editorial], New Eng J Med numerous cases of patients with violent behaviour, when B12 was 1988; 318:1752-54. However, about one-third of this vitamin's replenished (with or without other changes in life), violent molecule is not cobalamin, but metabolically inactive crinoids behaviour disappeared.” which may be effective for bacteria but do not serve as "The only question now," writes Dommisse, "is, what haemopoietic agents; see J. S. Bland, Preventive Medicine proportion of cases of mood-disorder is caused by B12-deficiency Update, October 1994. See also Addendum.) Having a quality laboratory measure serum B12 is an replenishment process. Simply supplementing B12 "in the dark" mark badly. Intramuscular injection of B12 also has yielded seeming miracle cures in still other desperate illnesses. Further, in numerous cases of patients with violent behaviour, when B12 was replenished (with or without other changes in life), violent behaviour disappeared.” "The only question now," writes Dommisse, "is, what proportion of cases of mood-disorder is caused by B12-deficiency 26 = NEXUS essential part of the could miss the www.nexusmagazine.com OCTOBER — NOVEMBER 2007