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AIDS: The Selenoenzyme Solution functions in HIV infection by sulfur supplemen- _ plasma and intracellular levels of thyroxine and tation: two randomized trials", J Mol Med 2000; __tri-iodothyronine in thyroidectomized thyroxine- Seyler 1988; 369(5):337-340. 78(1):55-62. treated rats", J Endrocrin 1992; 133:45-49. 69. Murray, M.F, "Niacin as a potential AIDS 78. Noyer, C.M. and others, "A double-blind 87. Hawkes, W.C. and others, "Effect of dietary preventative factor", Med Hypotheses 1999; placebo-controlled pilot study of glutamine ther- _ selenium on mood in healthy men living in a 53(5):375-379. apy for abnormal intestinal permeability in metabolic research unit", Biol Psychiatry 1996; 70. Sidibe, S. and others, "Effects of serotonin patients with AIDS", Am J Gastroenterol 1998; 39:121-128. and melanin on in vitro HIV-1 infection", J Biol 93(6):972-975. 88. Finley, J.W. and others, "Adequacy or Regul Homeost Agents 1996; 10(1):19-24. 79. Shabert, J.K. and others, “Glutamine-antiox- deprivation of dietary selenium in healthy men: 71. Peretz, A. and others, "Lymphocyte idant supplementation increases body cell mass clinical and psychological findings", J Trace response is enhanced by supplementation of in AIDS patients with weight | arandom- Elem Exp Med 1998; 11:11-27. elderly subjects with selenium-enriched yeast", ized double-blind controlled trial", Nutrition 89. Bunk, M.J. and others, "Evidence for an Am J Clin Nutr 1991; 53(5):1323-1328. 1999; 15(11/12):860-864. impairment in conversion of methionine to cys- 72. Porter, E.K. and others, "Uptake of seleni- 80. Kohler, H. and others, op. cit. teine in the Se-deficient chicken", Proc Soc Ex um-75 by human lymphocytes in vitro", J Nutr 81. Zangerle, R. and others, "Effective antiretro- Biol Med 1981; 167:87-93. 1979; 109(11):1901-1908. viral therapy reduces degradation of tryptophan 90. Braverman, E.R. (with C.C. Pfeiffer), The 73. Wang, R.D. and others, “Investigation of the in patients with HIV-1 infection", Clin Immunol Healing Nutrients Within: Facts, Findings and effect of selenium on T-lymphocyte proliferation — 2002; 104(3):242-247. New Research on Amino Acids, Keats and its mechanisms", J Tongji Med Univ 1992; 82. Murray, M.F. and others, "Increased plasma — Publishing, New Canaan, 1987. 12(1):33-38. tryptophan in HIV-infected patients treated with 91. Rhoads, M., "Glutamine signalling in 74, Baum, MLK. and others, "High risk of HIV- pharmacologic doses of nicotinamide", Nutrition intestinal cells", J Parenter Enteral Nutr 1999; related mortality is associated with selenium 2001; 17(7-8):654-656. 23(5 Suppl):S38-40. deficiency", J Acquir Immune Defic Syndr Hum 83. Baum, M.K., op. cit. 92. Ward, D.E., The AmFAR AIDS Handbook: Retroviral 1997; 15(5):370-374. 84. Foster, H.D., "AIDS and the 'selenium-CDR the Complete Guide to Understanding HIV and 75. De Rosa, S.C. and others, "N-acetylcysteine _T cell tailspin': The geography of a pandemic", AIDS, W.W. Norton, New York, 1999. replenishes glutathione in HIV infection", Eur J Townsend Letter for Doctors and Patients 2000, 93. Braverman, E.R., op. cit. Clin Invest 2000; 30(10):915-929. 209:94-99. 94. ibid. 76. James, J.S., "NAC: First Controlled Trial, 85. Bourdoux, P.P. and others, "Biochemical 95. Murray, M.F. and others, "HIV infection Positive Results", AIDS Treatment News 1996; thyroid profile in patients infected with the decreases intracellular nicotinamide adenine din- 250:1-3, posted at human immunodeficiency virus", Thyroid 1991; _ ucleotide (NAD)", Biochem Biophys Res http://www.aids.org/immunet/atn.nsf/ 1:149. Commun 1995; 212(1):126-131. page/ZQX25002.html. 86. Geelhoed-Duijvestijn, P.H. and others, 96. Foster, H.D., 2000, op. cit. 77. Breitkreutz, R., "Improvement of immune "Effect of administration of growth hormone on 97. Email to author, September 25, 2003. Seyler 1988; 369(5):337-340. 69. Murray, M.F, "Niacin as a potential AIDS preventative factor", Med Hypotheses 1999; 53(5):375-379. 70. Sidibe, S. and others, "Effects of serotonin and melanin on in vitro HIV-1 infection", J Biol Regul Homeost Agents 1996; 10(1):19-24. 71. Peretz, A. and others, "Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast", Am J Clin Nutr 1991; 53(5):1323-1328. 72. Porter, E.K. and others, "Uptake of seleni- um-75 by human lymphocytes in vitro", J Nutr 1979; 109(11):1901-1908. 73. Wang, R.D. and others, "Investigation of the effect of selenium on T-lymphocyte proliferation and its mechanisms", J Tongji Med Univ 1992; 12(1):33-38. 74. Baum, M.K. and others, "High risk of HIV- related mortality is associated with selenium deficiency", J Acquir Immune Defic Syndr Hum Retroviral 1997; 15(5):370-374. 75. De Rosa, S.C. and others, "N-acetylcysteine replenishes glutathione in HIV infection", Eur J Clin Invest 2000; 30(10):915-929. 76. James, J.S.,"NAC: First Controlled Trial, Positive Results", AIDS Treatment News 1996; 250:1-3, posted at http://www.aids.org/immunet/atn.nsf/ page/ZQX25002.html. 77. Breitkreutz, R., "Improvement of immune NEXUS +75 FEBRUARY — MARCH 2004 www.nexusmagazine.com