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FIGURE 1: The effect of vitamin C on cholesterol catabolism in guinea pigs tested. =e RESULTS OF NEW DIET OF VITAMIN C | CHOLESTEROL | CHOLESTEROL Tattered typ Mile mlatintdy) nec aaptst GUINEA PIGS MG/100G MG/100G TRANSFORMED | Of the French Paradox, Dr Serge Renaud, INTO BILE SALTS of the French National Institute of Health LIVER BILE BLOOD] LIVER MG/24H/KG and Medical Research, decided to find out what was the relation between wine NORMAL and platelet aggregation. From 10 MG VIT.C/24H 8.2 21.6 Professors Brun and Bourzeix of the French National Agronomical Research DEFICIENT Institute in Narbonne, Renaud obtained 0.5 MG VIT.C/24H 1.6 4.7 samples of standardised normal wine (with 6% alcohol), and of wine without THROMBOSIS alcohol. He also contacted Masquelier and obtained grape seed Cardiovascular integrity does depend on an unimpeded blood __ extract from Centre Expérimentation Pharmaceutique (CEP). flow through the vascular system, especially through the heart Dr Renaud then separated his test animals into several groups muscle and the brain. One of the circulation-impeding mecha- _and let them have free access to water (control group), red wine, nisms is blood clotting or thrombosis. white wine, and several beverages he concocted—such as water Thrombosis is a lifesaving mechanism in the case of wounds. with 6% alcohol, and water with 6% alcohol plus 0.03% grape Should the blood not clot, we would bleed to death. But some- seed extract added to it (the OPC level of red wine). times the blood has difficulties differentiating between a real Using pure water for his control group, Renaud measured, wound (trauma) and a pathological 'wound' such as extensive amongst other things, the effects of the drinking of alcohol+water, plaque formation, inflamed capillaries and other abnormal vascu- _ white wine and red wine on platelet aggregation and the rebound lar conditions. Such conditions form the perfect ground for initiat- effect. As expected, he found that all alcoholic beverages reduced ing the clotting of the blood. platelet aggregation. By contrast, when these same animals were A clot consists of fibrin threads that are bonded together under deprived of their alcoholic beverages for 18 hours, a marked the aggregating (clotting) influence of the so-called blood rebound effect of +124% was observed in the water+alcohol platelets. In pathological cardiovascular conditions, the formation group; a moderate increase of 46% was found in the white wine of blood clots mostly forms the onset of a severe crisis such as group; but no rebound at all was found in the red wine group, stroke or cardiac arrest. since aggregation was still reduced by 59% as compared to the : pure water group! (See Figure 3.) Te ee use of-dlechol FIGURE 2: These graphs show how OPC is vitamin C's real and effective companion. Guinea pigs were divided into five lots. Lot 2 was totally deprived of vitamin C, and that group succumbed can strongly reduce the tendency Of | in week five. Animals in Lot 3 were fed a vitamin C-deficient diet, and they lived twice as long as platelets to aggregate and contribute to _ | the totally deprived group. They succumbed in week 10. Lot 4 of the animals received a moderate- blood clotting. As such, alcohol reduces \y Saya ae but they eng pe H