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psilocin oxygen. PSYCHEDELIC DRUGS: SCIENCE AND SOCIETY + 37 When these mushrooms are ingested, the body removes a phospho- rous atom from the psilocybin, converting it to psilocin. Psilocin differs from DMT by only one oxygen. I like to think of psilocybin/psilocin as "orally active DMT." Another important tryptamine is 5-methoxy-DMT, or 5-MeO-DMT. It differs from DMT by the addition of only one methyl group and one 5-methoxy-DMT