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WINDING DOWN + 287 comer of the room before Laura and I arrived. She didn't want to move it back into the middle, its usual position. In addition, a visiting medical student had gone in to see her before we had introduced them, expressly against my wishes. Francine was extraordinarily attentive to anonymity issues, as she was a hospital employee. I would have first cleared with her the idea of a visiting student. Both of these irregularities—the bed placement and the student—set up high anxiety in me before we started. I nearly cancelled the study, but everyone seemed willing to carry on. Within 15 minutes of swallowing the psilocybin capsule, Francine became restless, frightened, and anxious. She accused me of "messing" with her mind. When her panicked cell-phone call to her husband dis- connected mid-conversation, she blamed my "mind waves" for the technical difficulties. Francine could tolerate only Laura in the room, and she asked if the medical student and I would step out for a while. While we were at the nurses’ station deciding how to proceed, Francine's hus- band raced down the hall, entered Room 531, and gathered her up. They pushed their way past Laura and flew out the Research Center's double doors before I got my bearings. As her husband ran past me, he said, "I've seen her this way before." I thought, "Now he tells me." The security guards came too late. While peaking on psilocybin, Francine was loose in Albuquerque. Thankfully, Francine remained under the watchful eye of her hus- band that day and came to no harm. Nevertheless, I needed to write up and send in reports to all the university committees and boards oversee- ing our research. The Food and Drug Administration and the National Institute on Drug Abuse also received copies of a narrative of the inci- dent. I referred to Francine's session as "an unfortunate, but not unexpected adverse reaction. Psychotic breaks do happen under the influence of these drugs, and they are nearly always brief. The volunteer recompensated quickly and is showing no ill effects of her session." Strictly speaking, this was true. Francine "felt fine" that next morn- ing and went back to work as if nothing had happened. However, she