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PROLOGUE + 9 My confidence was premature. In retrospect, a more cautious move to doubling it, to 0.4 mg/kg, would have been more reasonable. Thankfully, I didn't jump to 0.8 mg/kg, which would have happened had I followed Nils's suggestion that 0.2 mg/kg was a fourth of a full dose. This morning, both Philip and Nils were going to get 0.6 mg/kg IV DMT. It was sunny, cold, and windy in Albuquerque that day, and I was glad to be working inside. I entered Nils's room in the Research Center. He was lying under his sleeping bag, awaiting the first 0.6 mg/kg dose. Cindy already had placed a small needle into a forearm vein, the portal through which I would inject the DMT solution directly into his blood. She sat on his right side, and I on his left, where the tubing from the IV line dangled off his arm. Philip also was here; he was scheduled to receive the same dose later in the morning if all went well with Nils. He sat at the foot of the bed, curious about what Nils was to experience, and ready to provide moral support for all of us. Little did we suspect we'd need him for physi- cal backup, too. I infused the solution of DMT somewhat more quickly than I did for Nils's previous 0.2 mg/kg dose, over 30 seconds rather than a minute. I thought a faster injection might allow for less dilution of the DMT in the bloodstream. This then would generate higher peak levels of DMT in the blood and, therefore, the brain. After the infusion of drug was complete, Nils said excitedly, /can taste it... . Here it is! Immediately after blurting this out, he began tossing and turning un- der his sleeping bag. He then sat up with a start, exclaiming, I'm ut & 0 in, 8 g to vi 0. m it. ! He gazed at us, stunned and uncertain. Cindy and I looked at each other at the same time, realizing we had nothing into which he could throw up. We hadn't foreseen that our test subjects might need to vomit. He mumbled, But I didn't have any breakfast. . . so there's nothing to throw up. Nils became agitated and pulled the pillow and sleeping bag over his face. He curled into the fetal position, away from us and the blood