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89-001 passed. 89 ee a 1 here were two separate but overlapping fields upon which I would work out my attempt to perform a human DMT study. One was the clinical re- search realm; the other was regulatory. In this chapter I will focus on the science of the study: the actual research proposal. The next chapter will describe the labyrinth of boards and agencies through which the protocol The Human Research Ethics Committee at the University of New Mexico reviews any project intending to study humans. This committee stamps all such proposals with a number. The first two digits correspond to the year, and the next three digits reflect the order in which the protocol arrives. I submitted the DMT proposal in late 1988. It was the committee's first study up for review at their January meeting. Thus, it became 89-001. The first sentence, which I'd spent hours writing and rewriting the month before, trying to find the perfect opening line, read: "This project will begin a reexamination of the human psychobiology