PIHKALAnthologyShulgin_page_902

PIHKALAnthologyShulgin | page 902 | https://thedailydialectics.com/pdfs/education/chemistry/phenylethylenes/PIHKALAnthologyShulgin/PIHKALAnthologyShulgin.pdf

171 2-TOM; 5-METHOXY-4-METHYL-2- METHYLTHIOAMPHETAMINE SYNTHESIS: To a solution of 64.8 g of o-cresol and 56 g dimethyl sulfoxide in 300 mL Et2O, cooled with an external ice bath with vigorous stirring, there was added 40 mL chlorosulfonic acid dropwise over the course of 30 min. The cooling bath…